“Tangled” by James W. Lewis

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by James W. Lewis

Genre: Mystery, Thriller & Suspense/YA/Crime Fiction/Murder

2.99 at time of posting!

Welcome to the Monte Clara High Class of 2005 Reunion. Home of the Blue Devils.

Someone will cheat with an old flame.

Someone will reveal a gruesome, dark secret.

And someone might die.

At this epic party, everyone is wearing a mask, but who will get the last laugh?

TANGLED is a gripping psychological suspense with a twisted ending that will surprise and satisfy you at every turn.

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Fibromyalgia and Pain Killers?

I don’t know anyone with Fibromyalgia who’s found pain relief with Advil, Aspirin, or Tylenol. If any of them have worked for you, please share your dosage routine! 🙂

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Of primary concern for sufferers of fibromyalgia, of course, is the issue of pain killers and which are going to be most effective for your pain. There are different symptoms of the syndrome, but pain is the most pertinent condition. Effective pain relief can come from over-the-counter, prescription drugs or a combination. We present the 6 of the best fibromyalgia pain killers.

6 Fibromyalgia painkillers


Advil is a brand of ibuprofen, first developed in 1962.  It is a type of non-steroidal anti-inflammatory drug or NSAID. There are different brands of ibuprofen, but Advil is one of the best known. Similar to Tylenol, Advil is used for pain or fever relief. However, unlike Tylenol, Advil also soothes inflammation, making it one of the most effective fibromyalgia painkillers.

NSAIDs are among the most common pain relief medicines in the world. Over 30 million Americans use them every day to soothe headaches, sprains, arthritis symptoms, and other aches and pains. And, because of the anti-inflammatory abilities that NSAIDs have, they can also lower fever and reduce swelling.

NSAID drugs work by inhibiting cyclooxygenase-1 (COX-1), the chemical responsible for production and release of prostaglandins, which are, in turn, responsible for pain and fever. They also inhibit cyclooxygenase-2 (COX-2), which is responsible for inflammatory response.

These drugs are very effective for relief of pain caused by inflammation. Unfortunately, while the causes of fibromyalgia are still a bit of a mystery, it is known that it is not caused by inflammation. While these drugs have been prescribed often for fibromyalgia pain, they haven’t actually been all that effective on their own. However, NSAIDs have seen success in combination with other pain relievers.


Plain old Aspirin is also a NSAID like Advil, and it’s also one of our favorite fibromyalgia painkillers. The chemical name of Aspirin is acetylsalicylic acid or ASA for short. The use of willow and other salicylate-rich plants has an ancient history, being used by the ancient Sumerians. More recently, ASA in its pure form was distilled in 1899 by a scientist working for Bayer. There are also other brands available such as Bufferin, Entrophen and house brands. Like Advil, because it has anti-inflammatory properties, it can provide fever and pain relief. However, unlike either Tylenol or Advil, Aspirin also works to thin the blood and is therefore often used to prevent stroke and heart disease.

As part of the NSAID class of drugs, Aspirin inhibits COX-1 and COX-2 to provide relief from pain, fever, and inflammation. While most NSAIDs also inhibit platelets in the blood, Aspirin does so irreversibly for eight to ten days, the full lifespan of the platelet. It is this which gives it the ability to act as a blood-thinner, but can also make you more prone to bleeding.

Aspirin is generally safe, but children under 18 years of age should avoid it. While the side effect that might cause Reye’s syndrome is rare and only occurs in very specific circumstances, it is also very serious. Since there are other types of painkillers available, it is easier for children to simply avoid the drug altogether. It should also be noted that while there are products called “baby aspirin” or “low-dose ASA.” In spite of the names, these should also be avoided for children. These products are actually blood-thinners for adults to take to prevent heart disease and stroke.


The generic name of Tylenol is acetaminophen and it’s also on our list of fibromyalgia painkillers. This drug was discovered and marketed in 1956. It is called acetaminophen in the US, Canada and Japan, and paracetamol elsewhere. Unlike Advil and Aspirin, Tylenol is not in the NSAID category. Because it works on the nervous system instead of inflammation, it is more effective than NSAIDs for fibromyalgia pain.

Tylenol is used for pain or fever relief, but it has no anti-inflammatory action. Therefore, it won’t affect any underlying inflammation that can cause pain. Conversely, it can have a greater effect on pain like fibromyalgia where the pain is brought on by conditions in the nervous system rather than inflammation.

Tylenol is a safe drug to take for pain during pregnancy or lactation. That is because though it can be detected in breast milk, no adverse effects on either mothers or infants have been reported. Therefore, it is considered to be the first choice painkiller in pregnancy and lactation.

Acetaminophen is generally considered a very safe drug because it has few interactions with other drugs. It has also been around for a long time, so healthcare professionals are very familiar with it.  However, this can lead to a significant risk of overdose with the drug. First, because of the way it is perceived, it can mean that people are not as cautious with it as they really need to be. Because fibromyalgia pain is ongoing, it seems likely that, in an attempt to relieve pain, a person might be tempted to take more of the drug than is recommended.

Also, acetaminophen overdose can be quite serious. The symptoms of overdose include nausea, diarrhea, abdominal pain and jaundice. It also has several symptoms that may easily blend with symptoms that a patient is already suffering because of fibromyalgia and can, therefore, be easily missed.

Finally, it can be very easy to overdose on acetaminophen accidentally. This is because the drug is often included in other kinds of drugs. For example, you might be taking Tylenol for your fibromyalgia pain, and then catch a cold. Cold medication often also includes acetaminophen.

Acetaminophen is also sold in combination with opioid and other drugs.

Like ibuprofen and ASA, there are generics and other brands which have acetaminophen as the main active ingredient. They are virtually the same thing as Tylenol, and so it’s up to you which brand you want to use. If cost is an issue, you may want to buy the house brand acetaminophen, which is generally cheaper than the brand name Tylenol.


Unfortunately, there has been a long history of fibromyalgia being treated as a psychosomatic condition, so naturally, you might be suspicious if your doctor prescribes an antidepressant as one of the fibromyalgia painkillers. However, there has been a great deal of success in treating pain through tricyclic antidepressants like Amitriptyline.

It is believed that this is because the mechanism for fibromyalgia pain is chemically based on the neurotransmitters that carry pain signals to the brain. Many of these same neurotransmitters are involved in depression, which helps explain why antidepressants can help with fibromyalgia pain.

Unlike Tylenol, Aspirin, and Advil, Amitriptyline is not available over-the-counter. It is only available through a prescription. The drug can also help with sleep issues that come with fibromyalgia. So it can not only help with pain, but help you get more and better sleep.

It’s also not much of a surprise if the chronic pain of fibromyalgia might have made you depressed. Because there is generally a linkage between physical and emotional health, it will be helpful if it’s possible to elevate your mood. So in another way, an antidepressant can help with fibromyalgia suffering.


Lyrica is an oral medication that is classified as an anti-seizure or anti-convulsant drug. Lyrica is the trade name of the drug Pregabalin and it’s one of the more effective fibromyalgia painkillers. It was the first drug approved by the FDA for treatment of fibromyalgia. Like Amitriptyline, Lyrica is not an over-the-counter drug and must be prescribed.

Lyrica binds to a part of the nerves and it is thought that this reduces the ability for nerves to send pain messages to each other; it slows down impulses in the brain that cause seizures and affects chemicals in the brain that send pain signals across the nervous system.

Again, like Amitriptyline, the anticonvulsants work on the nervous system to relieve pain. The drug will reduce the number of pain signals that are sent to the brain. Fibromyalgia is believed to be caused, at least in part, by nerves being effectively “hyperactive” and so sending too many signals. What anticonvulsants do is calm the nerves and cause them to send fewer signals. This helps them prevent seizures in other conditions and also helps relieve pain in fibromyalgia.


There is little doubt that opioids do the job, and they will almost definitely be one of the most effective fibromyalgia painkillers. However, they also carry a very significant risk of creating dependence. For this reason, while there is very little question that opioids are effective, it is generally seen as a measure to be taken only after other treatments have been tried.

However, because antidepressants and anticonvulsants can take several days to take effect, opioids are sometimes prescribed in conjunction with other drugs. Also, where other options aren’t effective at relieving pain, long-acting opioids are often prescribed to stay on top of the pain while other solutions are explored.

While there are drugs with a higher success rate than others, it is also important to note that what works for one person may not work for another. One single drug won’t work for everyone. Conversely, a drug that may work for you won’t necessarily work for other people. To a certain extent, it will require some investigating and some trial and error.



The preceding article is from FibromyalgiaTreating.com and posted here for sharing purposes only. No copyright infringement is intended.

“The Workers of Iniquity: A C.T. Ferguson Private Investigator Mystery (The C.T. Ferguson Mystery Novels Book 3)” by Tom Fowler

Workers of Iniquity cover

The Workers of Iniquity: A C.T. Ferguson Private Investigator Mystery (The C.T. Ferguson Mystery Novels Book 3)

by Tom Fowler

Genre: Mystery & Suspense/Technothriller/Crime Fiction/Pulp

FREE at time of posting! Kindle Unlimited!


A bankrupt client. A missing husband.

One cyber sleuth will follow the money trail to the root of all evil.

Private investigator C.T. Ferguson believes justice shouldn’t come with a price tag. As a trust fund baby and former hacker, he uses his resources to track down criminals who prey on society’s most vulnerable members.

When an old acquaintance falls on hard times, he vows to solve the mystery of her missing husband and empty bank account. Following the digital trail, he uncovers a grisly hotel room crime scene.

But the husband’s ruthless loan shark won’t draw the line at one dead body. When the clues take an unexpected turn, C.T. realizes he’s stumbled onto a sinister black market where humanity’s worst sins are sold to the highest bidder.

The people who run the criminal syndicate don’t care about dead private investigators.

You’ll love this mystery novel because of its fast-paced action, cyber-savvy sleuth, and spine-tingling suspense.

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##GuestPost “Redneck’s Revenge (The Isabel Long Mystery Series Book 2)” by Joan Livingston

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Redneck's Revenge coverHer next case. She’s in it for good.

Isabel Long is in a funk months after solving her first case. Her relationship with the Rooster Bar’s owner is over. Then the cops say she must work for a licensed P.I. before working solo.

Encouraged by her ‘Watson’ — her 92-year-old mother — Isabel snaps out of it by hooking up with a P.I. and finding a new case.

The official ruling is Chet Waters, an ornery so-and-so, was passed out when his house caught fire. His daughter, who inherited the junkyard, believes he was murdered. Topping the list of suspects are dangerous drug-dealing brothers, a rival junkyard owner, and an ex-husband.

Could the man’s death simply be a case of redneck’s revenge? Isabel is about to find out.

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~ Guest Post ~

Sex in Redneck’s Revenge: PG13

Yes, there’s six in my new mystery, Redneck’s Revenge. It makes sense because I write about adults and sex is a part of what they do. But it is a delicate matter when writing about something oh-so personal and with the potential to be vulgar. Let’s say I give enough so my readers can use their imagination.

There are no graphic descriptions of body parts. Nothing throbs. The sex scenes aren’t icky or embarrassing. My characters are consenting adults who are having a good old time in the sack, and in Redneck’s Revenge, they are mature consenting adults.

Specifically, Isabel, the book’s protagonist, has been a widow for a little more than a year. She grieved for him properly and then she was ready to have a relationship with all the fixings. How did she put it? It’s time to do something foolish or at least, have fun.

It’s all a part of her transformation from a long-time journalist to an amateur sleuth. She has one case under her belt — check out Chasing the Case for that — and has signed on for another.

Isabel is what the French call une femme d’un certain age. I didn’t want a protagonist who was some sweet, young, but a woman with experience.

That’s what she does. And she doesn’t have to look far even in that dinky hilltown where she lives. Try the town’s only bar, the Rooster.

I’m not going to spoil things by giving away who Isabel has sex with in Redneck’s Revenge. (Actually he even has a rival.) But I will say there’s a lot of playful banter between Isabel and her lover, but then again she is a bit on the sassy side.

Then there’s Annette Waters, who hires Isabel for this case. She owns a garage and junkyard. Let’s say, Annette likes to play around and she’s not shy about it. Here is a conversation between Isabel, who works part-time at the Rooster Bar, and Annette, who’s there for fun.

“But I’m not giving up just yet,” I tell Annette. “How about I come over tomorrow to dig around?”

“That works for me. Make it early afternoon, say one or later, after the sun hits that spot for a while. Make it easier.” She smirks. “Besides, I’m expectin’ company tonight.”

“Anyone I know?”

“Not sure. Haven’t picked him out yet.”

“We’ve got a full house, so your chances are good.”

“Yeah. And if I ain’t as picky as you.”

One more thing on writing about sex: I will admit a few of my adult kids were uncomfortable about the sex scenes in my other books. So, when I gave my now 94-year-old mother a copy, I added this warning, “Mom, there’s a bit of sex in it.” (By the way, she is the inspiration for Isabel’s mother, who is her ‘Watson’ in this series.)

Here’s what she told me after reading it: “Oh, I’ve read a lot worse than that.”

Really Mom?


Author Bio  Joan Livingston

Joan Livingston is the author of novels for adult and young readers. Redneck’s Revenge, published by Crooked Cat Books, is the second in the mystery series featuring Isabel Long, a long-time journalist who becomes an amateur P.I. The first is Chasing the Case.

An award-winning journalist, she started as a reporter covering the hill-towns of Western Massachusetts. She was an editor, columnist, and most recently the managing editor of The Taos News, which won numerous state and national awards during her tenure.

After eleven years in Northern New Mexico, Joan returned to rural Western Massachusetts, which is the setting of much of her adult fiction, including the Isabel Long series.

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Litsy: JoanLivingston



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(Open Internationally)

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*Terms and Conditions –Worldwide entries welcome.  Please enter using the Rafflecopter box below.  The winner will be selected at random via Rafflecopter from all valid entries and will be notified by Twitter and/or email. If no response is received within 7 days then I reserve the right to select an alternative winner. Open to all entrants aged 18 or over.  Any personal data given as part of the competition entry is used for this purpose only and will not be shared with third parties, with the exception of the winners’ information. This will be passed to the giveaway organizer and used only for fulfilment of the prize, after which time I will delete the data.  I am not responsible for dispatch or delivery of the prize.


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“LullaY: Portland ME, a Christmas Novella” by Freya Barker

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LullaY: Portland ME, a Christmas Novella

by Freya Barker

Genre: Romance/Holidays

PreOrder for 99¢! Releases November1, 2018

Faith failed him.

Ambition drove her.

Serendipity brought them together.

They’ve never met, but their paths run in the same direction—home for the holidays.
Yet their reasons for leaving are as different as the reasons they return.

Meeting by chance along a 1400 mile stretch of highway when a snowstorm grinds traffic to a halt, they have no choice but to jointly ride it out.

Exposing a common thread, leading them from the past to the present, it’s through the innocent eyes of a toddler, they discover a future.

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